Virologie Studies in Human Leukemia and Lymphoma: The Herpes-type Virus

Selected background information is presented and discussed in the light of newer facts and leads from studies constituting a broad effort aimed at determining whether viruses similar (or different) to those known to be associated with the induc tion of leukemia and lymphoma in laboratory and domestic animals are also involved in the etiology of human leukemia and lymphoma. Emphasis was placed on studies concerning the establishment and experimental use of hematopoietic cell lines and of a herpes-type virus frequently associated with the cultures. Based on information published or contributed to the Special Virus-Leukemia Program of the National Cancer In stitute, as of July 1967, over 125 cell strains have been estab lished from patients with cancer or other diseases and from nondiseased controls. At least 61 of the "cancer" and 5 of the "noncancer" derived lines show herpes-type virus by electron